Treatment-related Bone Loss

Several medications, essential for managing serious diseases, are associated with bone loss and/or an increased risk of fractures.

Certain medications, while vital for managing other conditions, can have side effects that weaken bones and increase fracture risk.

For example, Prednisone, often prescribed for conditions like rheumatoid arthritis, can lead to significant bone loss if used long-term (more than 3 months) at doses of 7.5 mg/day or higher. Medications used to treat prostate cancer (Androgen Deprivation Therapy), can also weaken bones. Also, medications which are crucial for hormone receptor-positive breast cancer (Aromatase Inhibitors), are also linked to reduced bone density.

Additionally, treatment for HIV/AIDS (antiretroviral) can impact bone health, leading to a higher risk of osteoporosis and fractures.

It is vital for individuals to recognise the potential side effects of these medications and discuss with their healthcare providers how they can be minimised.